The Khun Amphaiphanich Building was originally the old residence of Khun Amphaiphanich and his wife, Nang Amphaiphanich, who were prominent figures from Si Sa Ket. Constructed in 1925 by Vietnamese and Chinese craftsmen, the building showcases a blend of Vietnamese and Chinese architectural styles. Locally, it is commonly referred to as "Tuk Khun Amphaip." Its remarkable artistic, architectural, and historical significance has led the Fine Arts Department to officially register it as an important national heritage site.